ReishiGanoderma lucidum
the most-studied of the threeStart here. Reishi is the only mushroom on this page with a substantial body of randomised human trials, whatever the outcome measured.
- Extracción
- Agua caliente 10:1
- Beta-D-glucanos
- ≥30%
El reishi encabeza la lista como el hongo más estudiado que comercializamos, con 17 ensayos clínicos agrupados en una revisión de 2025. El maitake ocupa el segundo lugar, con ensayos aleatorizados en adultos sanos. El chaga es el tercero: la investigación de laboratorio vincula su actividad antioxidante y antiinflamatoria con compuestos que el cuerpo fructífero extrae del abedul, y cuenta con siglos de uso diario. Los tres son extractos en agua caliente 10:1, analizados con un 30%, 30% y 10% de betaglucanos respectivamente.
Start here. Reishi is the only mushroom on this page with a substantial body of randomised human trials, whatever the outcome measured.
Second, and the one to pick if you cook. Maitake is a genuinely good culinary mushroom as well as an extract.
Third, and honestly ranked. Chaga has the most enthusiastic marketing in this category and the least human evidence behind it.
Ganoderma lucidum
Start here. Reishi is the only mushroom on this page with a substantial body of randomised human trials, whatever the outcome measured.
Grifola frondosa
Second, and the one to pick if you cook. Maitake is a genuinely good culinary mushroom as well as an extract.
Inonotus obliquus
Third, and honestly ranked. Chaga has the most enthusiastic marketing in this category and the least human evidence behind it.
What customers report. Individual experience varies; none of this is a clinical claim.
The widest survey of the Reishi literature: 17 clinical trials covering 971 participants, at doses from 200 to 11,200 mg a day. Pooled analysis found significant improvements in BMI, serum creatinine, glutathione peroxidase and resting heart rate. Many other markers did not move, and the reviewers rate the certainty of the underlying trials as low and call for better-designed studies, which is the usual state of a field this active and this young.
Food Science & Nutrition · 2025Forty-seven healthy adults aged 60 and over ate bread containing 50 g of maitake daily for eighteen weeks. One strain produced a significant improvement on the Japanese Montreal Cognitive Assessment against placebo, and natural killer cell activity rose in the same group and tracked the cognitive score. Two strains were tested and one moved the needle, which tells researchers exactly where to look next.
Journal of Nutritional Science and Vitaminology · 2026A review pulling together the modern research on Chaga: antioxidant, anti-inflammatory and immunomodulatory activity, traced to the melanin, polysaccharides and triterpenes the conk accumulates from the birch it grows on. A consistent laboratory picture, and human trials are the natural next step.
Mycology · 2024